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Trial of Regeneron’s Covid-19 Antibody Drug Is Halted in Sickest Hospital Patients – The Wall Street Journal

Suspension is due to safety concern; testing continues in patients with less serious cases

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Regeneron Pharmaceuticals Inc. suspended testing of its Covid-19 antibody drug in the sickest hospitalized patients because of a safety concern, the latest setback for antibody-drug trials in patients with the most advanced disease.
Regeneron said Friday it is pausing enrollment of hospitalized Covid-19 patients receiving mechanical ventilation or high-flow oxygen, after an independent monitoring committee observed a potential safety signal and an unfavorable risk/benefit profile at this time.
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